Enzyme now integrates seamlessly with Claude Desktop through Anthropic’s Model Context Protocol, allowing you to surface relevant notes from your knowledge base directly in your AI conversations. Here’s a quick guide to getting started.
Setup
Install Enzyme to Claude Desktop:
- Navigate to
Enzyme Settings > Model Context Protocol Setup
- Click
Enable Claude MCP Integration
- Restart Claude Desktop
- Confirm Enzyme is running in Claude Desktop:
Settings > Developer > enzyme
should show the Enzyme MCP server running
From Generated Recipes to Using MCP in Claude Desktop
Generating a recipe in Enzyme can continue as a conversation in Claude Desktop. Here’s how to do it:
- Create a recipe in Enzyme: select an entity or two and click
Generate Recipe
- Click the copy button to the top right of the analysis. This will copy the analysis to your clipboard, formatted as a prompt with the entities to retrieve from your vault.
- Paste the prompt into Claude Desktop
Claude will agentically use its Enzyme MCP integration to retrieve the notes and incorporate them into its response.
Using Context in Conversations
You can also try crafting your own prompt like this to see Enzyme in action, replacing the tags and folder names with your own:
Grab my latest 30 notes tagged with #reflections and my most recent 10 notes from Readwise/, which should contain highlights from some articles I’ve read recently. What themes do you notice between my personal thoughts and my reading?
Claude will extract the contents from your notes and use them to generate a response. Just a tip: you can also specify rules for working with your knowledge base structure by using Claude Project notes.
What Makes This Powerful
Instead of manually uploading files or copying notes, Enzyme lets you:
- Reference any part of your knowledge base on demand
- Build conversations with deep context from your notes
- Spot connections across different types of content
- Keep your workflow uninterrupted
This is just the beginning of how Enzyme can enhance your knowledge workflows. Try it out and let us know how you’re using it!
Have questions or feedback? Feel free to reach out directly.